[3-(Methylsulfonyl)phenyl]-boronic acid

[3-(Methylsulfonyl)phenyl]-boronic acid - Names and Identifiers

Name	[3-(Methylsulfonyl)phenyl]-boronic acid
Synonyms	3-(Methylsulfonyl)Phenylboroni 3-(Methylsulfonyl)Phenylboronic Acid 3-(METHYLSULFONYL)PHENYLBORONIC ACID (3-Methylsulfonylphenyl)boronic acid 3-(METHANESULFONYL)PHENYLBORONIC ACID 3-(Methylsulfonyl)benzeneboronic acid 3-(METHYLSULPHONYL)BENZENEBORONIC ACID 3-(Methanesulfonyl)phenyl boronic acid 3-(methylsulfonyloxy)phenylboronic acid [3-(Methylsulfonyl)phenyl]-boronic acid Boronic acid, [3-(methylsulfonyl)phenyl]- (9CI)
CAS	373384-18-0
InChI	InChI=1/C7H9BO4S/c1-13(11,12)7-4-2-3-6(5-7)8(9)10/h2-5,9-10H,1H3

[3-(Methylsulfonyl)phenyl]-boronic acid - Physico-chemical Properties

Molecular Formula	C7H9BO4S
Molar Mass	200.02
Density	1.39±0.1 g/cm3(Predicted)
Melting Point	102-110°C
Boling Point	478.3±51.0 °C(Predicted)
Appearance	Powder
pKa	7.11±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
MDL	MFCD03092935

[3-(Methylsulfonyl)phenyl]-boronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Class	IRRITANT

[3-(Methylsulfonyl)phenyl]-boronic acid - Introduction

[3-(Methylsulfonyl)phenyl]-boronic acid is an organic boron compound with the chemical formula C7H9BO4S. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance:[3-(Methylsulfonyl)phenyl]-boronic acid is a white to light yellow solid.
-Solubility: It can be dissolved in anhydrous organic solvents, such as dimethyl sulfoxide, dimethyl formamide, etc.

Use:
-Catalyst:[3-(Methylsulfonyl)phenyl]-boronic acid is commonly used as a catalyst for organic synthesis reactions. For example, the introduction of a sulfonyl group on a phenylboronic acid compound can increase its newly added reactivity.
-Pharmaceutical research: It is also widely used in drug discovery and research, especially in the design and synthesis of anti-tumor compounds.
-chemical synthesis:[3-(Methylsulfonyl)phenyl]-boronic acid is an important intermediate for the synthesis of oxaloamphetamine and other organic compounds.

Preparation Method:
[3-(Methylsulfonyl)phenyl]-boronic acid can be prepared by reacting phenylboronic acid with 3-methylsulfonylbromobenzene. The reaction is usually carried out in a suitable solvent and at a suitable temperature for a period of time.

Safety Information:
Less information has been reported on the safety of [3-(Methylsulfonyl)phenyl]-boronic acid. In general, it is a relatively stable and safe compound under normal conditions of use. However, relevant safety practices should be followed for mass production and industrial use, including the wearing of personal protective equipment, the use of ventilated and sealed containers, etc. Any chemical should be used with care and stored properly to avoid contact with skin, eyes and inhalation of vapors. If contact or inhalation occurs, seek medical attention. When handling and using chemicals, reference should be made to the relevant safety data sheets and literature.

Last Update：2024-04-09 21:54:55